Not all forms of vitamin B12 and folate are equally effective. Conventional supplements often contain only synthetic forms of folic acid and vitamin B12, which the body must first convert into their biologically active forms before they can be utilised. Sunday Natural Vitamin B12 MH3A® plus Folate Complex Ultra delivers the full spectrum of bioactive, natural forms for both vitamins.
Conventional combination supplements of B12 and folate typically provide just one active ingredient per vitamin. Within our body and in natural foods, however, both occur in several active forms. Each form has a different effect and is absorbed through partially distinct metabolic pathways, meaning the optimal B12 or folate form can vary from person to person. By combining two premium active ingredient complexes containing all the active, natural B12 and folate cofactors, we ensure ideal absorption of both vitamins.
As the B12 pioneer who first introduced it, our Vitamin B12 MH3A® formula delivers vitamin B12 the way it naturally occurs in food, unlike many conventional B12 supplements: as a combination of all three natural, bioactive forms of vitamin B12 in optimal synergy. Each of these three forms fulfils distinct roles in the body and has its own area of focus. Our MH3A® formula contains all three forms of vitamin B12 in an equal, balanced ratio across five B12 active ingredients, providing comprehensive all-round support, mirroring how all three forms are always found together, both in the body and in nature's own food sources. On the market, almost all available supplements contain only one of the three B12 active ingredients: methylcobalamin, hydroxocobalamin or adenosylcobalamin.
In our Folate Complex Ultra formula, we've combined three premium folates for exceptional folate diversity. The two most bioactive L-methylfolates: the glucosamine salt and the highly bioavailable calcium salt. Both deliver 99.9% pure L-methylfolate and complement one another through quick, effective absorption of bioactive L-5-MTHF via distinct metabolic pathways. As a third ingredient, lemon peel extract provides the full spectrum of natural folates, offering seamless, comprehensive support modelled on nature itself. The glucosamine salt is a form in which methylfolate is bound to glucosamine to stabilise it, ensuring optimal shelf life and efficacy. Glucosamine is itself a valuable, natural component of various body tissues, adding further benefit to the overall effect. This form stands out for its previously unmatched bioavailability and can be utilised directly by the body. Owing to its exceptional purity, high stability and outstanding bioavailability, this glucosamine salt ranks among the two most valuable and effective forms of L-methylfolate available. The second premium active ingredient is highly bioavailable L-methylfolate as L-5-methyltetrahydrofolate, bound to a calcium salt in a special, particularly effective crystalline form. This ensures an extremely high absorption rate of the active ingredient L-5-MTHF. As a result, during first-pass absorption, the initial uptake step, 76% of the active ingredient can be absorbed into the bloodstream, where it's even able to cross the blood-brain barrier. With a minimum purity of 99.9% of the active (6S) isomer of L-methylfolate and its high stability, it stands as one of the two unrivalled premium forms of L-methylfolate.
Dissolving the tablets in the mouth offers the advantage that the vitamins can be absorbed directly through the oral mucosa via passive diffusion. This bypasses gut-related absorption issues and significantly increases bioavailability. Via this route, the vitamins also enter the bloodstream directly, without first having to pass through the liver, as would be the case with intestinal absorption.
Our premium tablets are made using natural guar bean fibre as their base. We entirely avoid the use of pressing aids such as magnesium stearate or coatings with sweeteners, colourings or gelatine.